EC Number |
Inhibitors |
Structure |
---|
6.2.1.4 | ADP |
- |
|
6.2.1.4 | zinc chloride |
- |
|
6.2.1.4 | valproyl-CoA |
25-50% inhhibition at 1 mM |
|
6.2.1.4 | valproyl-CoA |
25-50% inhibition at 1 mM |
|
6.2.1.4 | NaI |
41% inhibition at 10 mM, the CoAT activity is inhibited by applying NaI to exponentially growing cell cultures, but the colony-forming ability is not affected |
|
6.2.1.4 | ZnCl2 |
complete inhibition at 1mM |
|
6.2.1.4 | guanidinium hydrochloride |
inactivation at 0.5 M |
|
6.2.1.4 | more |
no inhibition by valproic acid |
|
6.2.1.4 | more |
not inhibited by valproic acid |
|
6.2.1.4 | Urea |
the Thermus aquaticus enzyme loses activity at 4-5.5 M urea, but it regains activity with increasing concentrations of urea, reaching 70% of its original activity in 8.5 M urea |
|