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EC Number
Inhibitors
Commentary
Structure
4,5-Dioxovalerate
competitive inhibition of pyridoxamine-phosphate form of the enzyme and mixed-type inhibition of the pyridoxal-phosphate form of the enzyme
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4-Amino-5-fluoro-pentanoic acid
-
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4-Amino-5-hexenoic acid
-
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4-Amino-5-hexynoic acid
-
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Aminooxyacetate
20 mM, 57% inhibition
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Aminooxyacetate
-
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cycloserine
20 mM, 43% inhibition
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D-penicillamine
20 mM, 9% inhibition
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gabaculine
0.005 mM, 83% inhibition. Irreversible inhibition which requires the presence of either glutamate-1-semialdehyde or 5-amino-4-oxopentanoate
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gabaculine
complete inactivation by gabaculine when the enzyme is exposed to 5-amino-4-oxopentanoate, levulinate or 4,5-dioxovalerate in absence of glutamate 1-semialdehyde
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Results 1 - 10 of 20 > >>