EC Number   |
Inhibitors |
Structure |
|---|
  4.1.1.84 | (R)-2-amino-4-methyl-N-(1-(naphthalen-1-yl)ethyl)-5-(3-(trifluoromethyl)phenyl)thiophene-3-carboxamide |
- |
   |
| 4.1.1.84 | (R)-5-methyl-3-(1-(naphthalen-1-yl)ethyl)-6-(3-(trifluoromethyl)-phenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
suppresses the proliferation of non-small cell lung cancer cells in two-dimensional and three-dimensional cell cultures, low micromolar level potency for inhibition of both MIF2 tautomerase activity and cancer cell proliferation |
|
| 4.1.1.84 | (S)-5-methyl-3-(1-(naphthalen-1-yl)ethyl)-6-(3-(trifluoromethyl)-phenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
- |
|
| 4.1.1.84 | 2-amino-4-methyl-N-[(naphthalen-1-yl)methyl]-5-(3-(trifluoromethyl)phenyl)thiophene-3-carboxamide |
- |
|
| 4.1.1.84 | 3-benzyl-5-methyl-6-(3-(trifluoromethyl)phenyl)thieno[2,3-d]-pyrimidine-2,4(1H,3H)-dione |
- |
|
| 4.1.1.84 | 3-benzyl-6-(2,4-dichlorophenyl)-5-methylthieno[2,3-d]-pyrimidine-2,4(1H,3H)-dione |
- |
|
| 4.1.1.84 | 3-benzyl-6-(3,4-dichlorophenyl)-5-methylthieno[2,3-d]-pyrimidine-2,4(1H,3H)-dione |
- |
|
| 4.1.1.84 | 4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid |
specifically inhibits DDT-induced PGE2 production in astrocytes |
|
| 4.1.1.84 | 4-hydroxyphenylpyruvate |
competitive |
|
| 4.1.1.84 | 4-iodo-6-phenylpyrimidine |
inhibition of DDT is efficient in attenuating DDT-induced astrocyte production of PGE2 following spinal cord injury |
|
