EC Number |
Inhibitors |
Structure |
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3.3.2.6 | more |
not: EDTA, dipicolinic acid |
|
3.3.2.6 | more |
not diethyl dicarbonate |
|
3.3.2.6 | more |
some enzyme inhibitors also affect the cytotoxicity of the anthrax lethal factor on macrophage cell lines |
|
3.3.2.6 | more |
not: PMSF, GEMSA, iodoacetamide |
|
3.3.2.6 | more |
leukotriene A4 inhibitors based on piperidine and piperazine scaffolds, overview |
|
3.3.2.6 | more |
structure-based drug discovery, inhibitor binding and molecular docking, overview |
|
3.3.2.6 | more |
inhibitor structure-function analysis, overview |
|
3.3.2.6 | more |
combined molecular docking and pharmacophore filtering assay for identification of chemical compounds that can simultaneously inhibit the human leukotriene hydrolase hLTA4H and the human leukotriene C4 synthase hLTC4S enzymes |
|
3.3.2.6 | more |
not inhibited by NI101, 2-(5-(benzyloxy)-1H-indol-3-yl)ethanaminium chloride, 2-(5-(naphthalen-2-ylmethoxy)-1H-indol-3-yl)ethanaminiumchloride, 2-(5-(naphthalen-1-ylmethoxy)-1H-indol-3-yl)ethanaminium chloride, 2-(5-(3-phenoxybenzyloxy)-1H-indol-3-yl)ethanaminium chloride, 2-(5-(2-(4-(4-nitrophenoxy)phenoxy)ethoxy)-1H-indol-3-yl)ethanaminium chloride, 2-(5-(2-(4-(2-nitrophenoxy)phenoxy)ethoxy)-1H-indol-3-yl) ethanaminium chloride, 3-(2-(5-(3-phenoxybenzyloxy)-1H-indol-3-yl)ethylamino)propanoic acid, and 3-(2-(5-(2-(4-phenoxyphenoxy)ethoxy)-1H-indol-3-yl) ethylamino)propanoic acid |
|
3.3.2.6 | more |
cigarette smoke exposure acidifies the airspaces and induced localization of the LTA4H protein into the nuclei of the epithelial cells. This results in accumulation of proline-glycine-proline in the airspaces by suppressing the LTA4H aminopeptidase activity |
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