EC Number |
Inhibitors |
Structure |
---|
3.2.1.62 | 2',4'-dinitrophenyl-2-deoxy-2-fluoro-beta-D-galactopyranoside |
inactivation of lactase hydrolase activity |
|
3.2.1.62 | 2',4'-dinitrophenyl-2-deoxy-2-fluoro-beta-D-glucopyranoside |
inactivation of phlorizin hydrolase activity |
|
3.2.1.62 | 2',4'-dinitrophenyl-2-fluoro-2-deoxy-beta-D-glucopyranoside |
rapidly inhibits phlorizin hydrolase activity by covalently binding to the glutamic acid residue of the active site, lactase activity more slowly inhibited, pre-incubation with glucal protects the lactase active site from inactivation |
|
3.2.1.62 | 2-fluoro-dinitrophenylglucoside |
specifically inhibits phlorizin hydrolase, lactase activity is inhibited slowly |
|
3.2.1.62 | 2-oxoglutaric acid |
50% inhibition of the tartaric acid-activated phlorizin hydrolase at 20 mM |
|
3.2.1.62 | Ca2+ |
about 78% residual activity at 1 mM |
|
3.2.1.62 | cellobiose |
inhibition of galactosylceramide hydrolysis |
|
3.2.1.62 | cellobiose |
- |
|
3.2.1.62 | cerebroside |
from brain, competitive inhibition of lactase activity, Ki: 1.11 mM |
|
3.2.1.62 | Co2+ |
about 18% residual activity at 1 mM |
|