EC Number   |
Inhibitors |
Structure  |
|---|
    3.1.1.79 | more |
polyunsaturated species of triacylglycerols containing 18:2 or 20:4 double bonds depress rates of oleate release by 70-75% below control values |
 |
| 3.1.1.79 | more |
hormone-sensitive lipase is knocked down by RNA interference or selectively inhibited |
|
| 3.1.1.79 | more |
insulin (5-10 ng/ml) induces down-regulation of HSL, dexamethasone (50250 nM) induces down-regulation of HSL, bovine growth hormone (50 ng/ml) induces down-regulation of HSL |
|
| 3.1.1.79 | more |
incubation with LDL augments the accumulation of cholesteryl ester in the HSL-deficient hepatocytes |
|
| 3.1.1.79 | more |
no inhibition by EDTA, poor effect by Triton X-100 |
|
| 3.1.1.79 | more |
not inhibitory: EDTa or EGTA, dithiothreitol at 5 mM |
|
| 3.1.1.79 | Zn2+ |
10 mM, complete loss of activity |
  |
| 3.1.1.79 | Cu2+ |
10 mM, 50-60% inhibition |
|
| 3.1.1.79 | Cu2+ |
10 mM, complete loss of activity |
|
| 3.1.1.79 | Co2+ |
45% inhibition at 1 mM |
|
