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Results 1 - 10 of 105 > >>
EC Number
Inhibitors
Commentary
Structure
(3,4-dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-tert-butoxycarbonylamino-phenyl ester
IC50: 3 nM
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(5-chloro-2-[([6-[4-(trifluoromethyl)phenoxy]pyridin-3-yl]carbonyl)amino]phenyl)boronic acid
potent HSL inhibitor with a significantly reduced bioactivation potential. Oral administration of compound exhibit an antilipolytic effect on rats at 3 mg/kg
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(5-fluoro-2-[([6-[4-(trifluoromethyl)phenoxy]pyridin-3-yl]carbonyl)amino]phenyl)boronic acid
potent inhibitor, in vitro and in cell with high selectivity for cholinesterases AChE and BuChE. The compound exhibits antilipolytic effect in rats at 1 mg/kg p.o. and does not show bioactivation
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(S)-4-isopropyl-3-methyl-2-[3-methylpiperidine-1-carbonyl]isoxazol-5[2H]-one
-
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2-methoxyphenyl 3,4-dihydroisoquinolin-2(1H)-ylcarbamate
IC50: 6400 nM
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2-propanol
80-90% inhibition
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3-(3,5-dichlorophenyl)-N,N-dimethyl-5-(methylsulfanyl)-1H-1,2,4-triazole-1-carboxamide
-
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3-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-1,3,4-oxadiazol-2(3H)-one
-
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3-(4-chlorophenyl)-N,N-dimethyl-5-(methylsulfanyl)-1H-1,2,4-triazole-1-carboxamide
-
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4-(acetylamino)phenyl morpholin-4-ylcarbamate
-
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Results 1 - 10 of 105 > >>