EC Number |
Inhibitors |
Structure |
---|
2.8.1.6 | more |
not inhibitory: pyridoxal 5-phosphate, deoxyadenosine |
|
2.8.1.6 | more |
5'-methylthioadenosine is not an inhibitor. Neither biotin nor iminobiotin is a significant inhibitor |
|
2.8.1.6 | Zn2+ |
1 mM, almost complete inhibition |
|
2.8.1.6 | Cu2+ |
1 mM, almost complete inhibition |
|
2.8.1.6 | Co2+ |
1 mM, almost complete inhibition |
|
2.8.1.6 | Fe2+ |
above 1 mM |
|
2.8.1.6 | Hg2+ |
1 mM, almost complete inhibition |
|
2.8.1.6 | S-adenosyl-L-homocysteine |
potent inhibitor |
|
2.8.1.6 | Cd2+ |
1 mM, almost complete inhibition |
|
2.8.1.6 | L-methionine |
product inhibition. The combination of both products in equimolar concentrations results in more than simple additive inhibition, suggesting that they bind cooperatively to the enzyme. |
|