EC Number   |
Inhibitors   |
Structure   |
|---|
 2.7.8.B13 | (+-)-1-deoxy-1-phosphonomethyl-myo-inositol |
Ino-C-P, competitive inhibition, 24% and 76% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | (+-)-1-deoxy-1-phosphonomethyl-myo-inositol |
leads to growth inhibition |
   |
 2.7.8.B13 | (+-)-1-deoxy-1-[(diethoxyphosphinyl)methyl]-myo-inositol |
Ino-C-P(OEt)2, 11% and 40% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | (+-)-1-deoxy-1-[(diethoxyphosphinyl)methyl]-myo-inositol |
Ino-C-P(OEt)2, leads to growth inhibition |
   |
 2.7.8.B13 | (+-)-1-O-sulfamoyl-myo-inositol |
16% and 45% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | 1D-myo-inositol 1-monophosphate |
4% and 45% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | 1L-1-deoxy-1-carboxymethyl-chiro-inositol |
7% and 41% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | 1L-1-deoxy-1-carboxymethyl-myo-inositol |
7% and 41% inhibition at 1 mM and 5 mM, respectively |
   |
 2.7.8.B13 | more |
chemical synthesis of four types of inositol 1-phosphate derivatives, all synthesized compounds inhibit PIP synthase activity. The phosphonate analogue of inositol 1-phosphate has the greatest inhibitory effect among the synthesized compounds examined, kinetic analysis. No substrate inhibition by 1L-myo-inositol 1-phosphate |
 |
 2.7.8.B13 | more |
no growth inhibition by (+-)-1-O-sulfamoyl-myo-inositol, 1L-1-deoxy-1-carboxymethyl-myo-inositol, and 1 L-1-deoxy-1-carboxymethyl-chiro-inositol |
 |