EC Number   |
Inhibitors |
Structure  |
|---|
    2.7.2.8 | more |
not inhibitory: D-arginine, agmatine, citrulline, L-canavanine, L-lysine, L-ornithine, guanidinium ions, urea at 1 mM, 37°C |
 |
| 2.7.2.8 | more |
the enzyme is L-arginine-insensitive |
|
| 2.7.2.8 | ATP |
- |
  |
| 2.7.2.8 | ADP |
- |
|
| 2.7.2.8 | ADP |
inhibitor of complex formation with PII protein |
|
| 2.7.2.8 | 2-oxoglutarate |
complete inhibition at 0.5 mM |
|
| 2.7.2.8 | L-arginine |
pH and temperature dependent, sigmoidal dependence on concentration of arginine, Hill coefficient of 4, 1 mM, 37°C, 95% inhibition |
|
| 2.7.2.8 | L-arginine |
only for N-acetylglutamate synthase activity |
|
| 2.7.2.8 | L-arginine |
less inhibitory in the presence of the PII protein |
|
| 2.7.2.8 | L-arginine |
sigmoidal arginine inhibition kinetics, feedback inhibition, indentification of the N-terminal arginine site, mutational analysis, the mobile alphaH-beta16 loop of the arginine site is the modulatory signal receiver, overview |
|
