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Results 1 - 7 of 7
EC Number
Inhibitors
Commentary
Structure
(6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
lactone isolated from Cryptocarya rugulosa, covalent inhibition
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(6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition
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(6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition
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2-methyl-4-amino-5-hydroxymethylpyrimidine
competitive inhibition
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more
stable to treatment with p-hydroxymercuribenzoate
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pyridoxine
inhibits competitively the phosphorylation of 2-methyl-4-amino-5-hydroxymethylpyrimidine
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rugulactone
selectively modifies the enzyme not at the active site cysteine, but on a remote cysteine residue
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Results 1 - 7 of 7