EC Number   |
Inhibitors  |
Structure |
|---|
    2.6.1.5 | (4-hydroxyphenyl)acetic acid |
74% inhibition with tyrosine at 3 mM and (4-hydroxyphenyl)acetic acid at 12 mM |
   |
| 2.6.1.5 | 2-aminooxyacetate |
- |
|
| 2.6.1.5 | 2-chloro-3-(5-{[(2,6-difluorobenzyl)oxy]methyl}-5-methyl-4,5-dihydro-1,2-oxazol-3-yl)-6-(propan-2-yl)pyridine |
1 mM: 79% inhibition of enzyme activity, 0.5 mM: 67% inhibition of enzyme activity, 0.25 mM: 44% inhibition of enzyme activity |
|
| 2.6.1.5 | 2-oxoglutarate |
substrate inhibition at high concentration |
|
| 2.6.1.5 | 2-oxoglutarate |
enzyme shows substrate inhibition |
|
| 2.6.1.5 | 3,4-dihydroxyphenylalanine |
- |
|
| 2.6.1.5 | 3,4-Dihydroxyphenyllactate |
strong inhibition of all the three TAT isoenzymes |
|
| 2.6.1.5 | 3-(3,4-Dihydroxyphenyl)-2-methylalanine |
- |
|
| 2.6.1.5 | 3-(5-{[(2,6-difluorobenzyl)oxy]methyl}-5-methyl-4,5-dihydro-1,2-oxazol-3-yl)pyridine-2-carbonitrile |
1 mM: 82% inhibition of enzyme activity, 0.5 mM: 46% inhibition of enzyme activity, 0.25 mM: 8% inhibition of enzyme activity |
|
| 2.6.1.5 | 3-methoxydopamine |
- |
|
