EC Number   |
Inhibitors |
Structure  |
|---|
    2.5.1.6 | more |
S-adenosyl(5')-3-methylthiopropylamine does not inhibit |
 |
| 2.5.1.6 | more |
overview of the regulatory properties, effect of L-methionine analogues and influence of L-methionine concentration on activating and inhibiting effects, effect of tripolyphosphate and p-hydroxymercuribenzoate |
|
| 2.5.1.6 | more |
addition of reducing agents has no effect; addition of reducing agents has no effect; addition of reducing agents has no effect |
|
| 2.5.1.6 | more |
MAT is inactivated after 6 h of incubation in hypoxia (3% O2) in rat hepatocytes, prevented by NG-monomethyl-L-arginine methyl ester. Hepatic MAT s a sensible target for free radicals in vivo |
|
| 2.5.1.6 | more |
reactive oxygen and nitrogen species induce the inactivation of MAT I/III |
|
| 2.5.1.6 | more |
no inhibition with cycloleucine, L-homocysteine, L-norleucine, L-cis-2-amino-4-methoxy-3-butenoic acid, S-adenosylhomocysteine, 5'-methylthioadenosine, sinefungin |
|
| 2.5.1.6 | more |
not inhibitory: (R)-methioninol, 1,3,7-trimethyluric acid, 6-methylpurine |
|
| 2.5.1.6 | more |
no effect on activity at 0.1 mM Ni2+ |
|
| 2.5.1.6 | more |
overexpression of yeast AdoMet synthase plus cap guanine-N7 methyltransferase affords greater resistance to sinefungin than either enzyme alone |
|
| 2.5.1.6 | ATP |
- |
  |
