EC Number   |
Inhibitors |
Structure |
|---|
   1.4.4.2 | Aminooxyacetate |
- |
   |
| 1.4.4.2 | Glycine methyl ester |
- |
|
| 1.4.4.2 | N-ethylmaleimide |
- |
|
| 1.4.4.2 | serine |
competitive inhibitor |
|
| 1.4.4.2 | 5,5'-dithiobis-(2-nitrobenzoic acid) |
complete inhibition |
|
| 1.4.4.2 | N-ethylmaleimide |
complete inhibition |
|
| 1.4.4.2 | S-nitrosoglutathione |
i.e. GSNO, the glycine decarboxylase complex, GDC activity is inhibited by S-nitrosoglutathione due to S-nitrosylation/S-glutathionylation of several cysteine residues, overview. The inhibition of GDC activity after GSNO treatment can be an indirect effect of ROS induced by inhibition of complex I |
|
| 1.4.4.2 | more |
inactivation after incubation with glycine in presence of aminomethyl carrier protein (H-protein), it is a suicide reaction of the P-protein as a side reaction of the glycine decarboxylation |
|
| 1.4.4.2 | Co2+ |
inhibition of glycine-CO2 exchange by binding of metal with H-protein-bound intermediate of glycine decarboxylation |
|
| 1.4.4.2 | Cu2+ |
inhibition of glycine-CO2 exchange by binding of metal with H-protein-bound intermediate of glycine decarboxylation |
|
