EC Number   |
Inhibitors |
Structure  |
|---|
   1.14.11.6 | Ni2+ |
binding structure with truncated enzyme mutant |
   |
| 1.14.11.6 | Uracil |
non-competitive inhibitor |
|
| 1.14.11.6 | Uracil |
inhibitor of the three reactions, 50% inhibition at 1 mM |
|
| 1.14.11.6 | 5-fluorouracil |
linear non-competitive inhibitor |
|
| 1.14.11.6 | 5-Bromouracil |
95% inhibition at 5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-Nitrouracil |
70% inhibition at 5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-Formyluracil |
competitive inhibitor with respect to thymine |
|
| 1.14.11.6 | 5-Formyluracil |
79% inhibition at 2.5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-Formyluracil |
competitive inhibitor with respect to 5-hydroxymethyluracil; competitive inhibitor with respect to thymine |
|
| 1.14.11.6 | 5-Hydroxymethyluracil |
competitive inhibitor against thymine, noncompetitive against oxygen |
|
