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EC Number
Inhibitors
Commentary
Structure
1.1.1.71
more
dithiothreitol and EDTA have no effect on either oxidative or reductive activity
1.1.1.71
more
the Fe2+-reconstituted Ni-PhADH was sensitively and rapidly inactivated by dioxygen gas. The enzyme is inactivated by the replacement of the ferrous ion in the active site with another metal ion such as a zinc ion, which has been considered an inhibitor of iron-activating group III ADHs
1.1.1.71
Mg2+
10 mM, 78% of initial activity
1.1.1.71
Mg2+
slight inhibition
1.1.1.71
Zn2+
10 mM, 79% of initial activity
1.1.1.71
Zn2+
14% residual activity at 1 mM
1.1.1.71
Ca2+
-
1.1.1.71
Cu2+
-
1.1.1.71
EDTA
10 mM, 20% inhibition
1.1.1.71
EDTA
5 mM, 20% inhibition; 5 mM, 80% of initial activity
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