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Results 1 - 10 of 97 > >>
EC Number
Inhibitors
Commentary
Structure
1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
half-maximal inhibition at 0.023 mg/ml
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2,2'-bithiophene-5-carboxylic acid
the inhibitor is identified by virtual screeening, 87% inhibition at 0.2 mM, competitive versus shikimate, uncompetitive versus NADP+. Flexible docking studies reveal that the inhibitor molecule makes interactions with catalytic residues
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2,2-bisepigallocatechin gallate
about 50% inhibition at 0.0025 mM
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2,4-Dichlorophenoxyacetic acid
-
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2-([2-([2-([2-(2,3-dimethylanilino)-2-oxoethyl]sulfanyl)-1,3-benzothiazol-6-yl]amino)2-oxoethyl]sulfanyl)-N-(2-naphthyl)acetamide
IC50: 0.0029 mM, competitive inhibition with respect to shikimate, noncompetitive to NADP+, potent antibacterial activity
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2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylic acid
31% inhibition at 0.2 mM
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2-[methyl[3-(trifluoromethyl)naphthalen-1-yl]amino]ethan-1-ol
49% inhibition at 0.2 mM
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3,5-Dihydroxybenzoate
moderate
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3-(2-naphthyloxy)-4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl 3-chlorobenzoate
IC50: 0.0039 mM, noncompetitive inhibition with respect to shikimate, competitive to NADP+
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3-(3-fluoropyridin-4-yl)-6-(phenoxymethyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole
-
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Results 1 - 10 of 97 > >>