Refine search

Search Inhibitors

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Image of 2D Structure
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 10 of 47 > >>
EC Number
Inhibitors
Commentary
Structure
ADP
-
Go to the Ligand Summary Page
AMP
-
Go to the Ligand Summary Page
Ca2+
84% residual activity at 1 mM
Go to the Ligand Summary Page
EDTA
83% residual activity at 1 mM
Go to the Ligand Summary Page
gallic acid
is a non-competitive inhibitor with respect to UDP-glucose and NAD+. It decreases specific activities of UGDH, but does not affect UGDH protein expression, thus UGDH activity is inhibited by polyphenols at the post-translational level. Gallic acid exerts strong antiproliferative activity in breast cancer cells. Heat inactivation of UGDH is accelerated to a greater degree by quercetin than by gallic acid. In the presence of gallic acid, the activity remaining after 30 min is 55% that of control
Go to the Ligand Summary Page
Mn2+
84% residual activity at 1 mM
Go to the Ligand Summary Page
more
no substrate inhibition, K+ is not inhibitory up to 500 mM, not inhibitory: dimethyldicarbonate, EDTA
Go to the Ligand Summary Page
more
in the presence of 0.12 mM 5-azido-UDP-glucose, 89% of the enzyme activity is lost after 5 min of photolabeling. When the enzyme is photolyzed in presence of 1 mM UDP-glucose, 11% of the enzyme activity is lost. 5-azido-UDP-glucose is photoinserting into a UDP-glucose-binding site on the human enzyme in a specific manner. Uracil, uridine, and glucose have a poor protective effect on the labeling, while UDP and UDP-glucose strongly inhibit photoinsertion
Go to the Ligand Summary Page
more
inhibition of human UDP-glucose dehydrogenase expression using siRNA expression vector in breast cancer cells
Go to the Ligand Summary Page
more
the enzyme from serotype K30 is not inhibited by NAD+, in contrast to Escherichia coli K-12
Go to the Ligand Summary Page
Results 1 - 10 of 47 > >>