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EC Number
Inhibitors
Commentary
Structure
6.5.1.2
KCl
inhibition by KCl occurs at greater than 30 mM (NH4)2SO
6.5.1.2
putrescine
-
6.5.1.2
methotrexate
IC50 of 0.008 mg/ml
6.5.1.2
cAMP
inhibits adenylation reaction
6.5.1.2
(NH4)2SO4
(NH4)2SO4 concentrations higher than 30 mM are inhibitory. At 100 mM KCl, concentrations of (NH4)2SO4 above 12 mM are inhibitory
6.5.1.2
doxorubicin
IC50: 0.0033 mM
6.5.1.2
doxorubicin
doxorubicin inhibits the ATP-dependent DNA ligase of bacteriophage T4 and the Escherichia coli NAD+-dependent ligase with a similar potency
6.5.1.2
Chloroquine
effective inhibitor
6.5.1.2
Chloroquine
-
6.5.1.2
Quinacrine
powerful inhibitor, exhibits good inhibition at nanomolar concentrations
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