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EC Number Inhibitors Commentary Structure
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.125-fluorocytidine KD value of 2.02 mM Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12artesunate - Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12Chloroquine - Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12Cidofovir KD value of ca. 40 mM Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12Cytosine arabinoside monophosphate KD value of 18.91 mM Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12EDTA 5 mM. Activity can be restored by the addition of Mg2+ to a concentration of 10 mM Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12more 5-(1,3-benzodioxol-5-ylamino)-5-oxopentanoic acid, 2-[(2,6-diaminopyrimidin-4-yl)sulfanyl]acetamide and 4-(5-amino-1,3,4-oxadiazol-2-yl)-1,2,5-oxadiazol-3-amine are inactive. Activity with compounds 2-amino-N-hydroxy-acetimidic acid, N-hydroxy-nicotinimidic acid, 5-bromo-thiophene-2-sulfonic acid amide, 4-bromobenzenesulfonamide and 4-(4-dimethylamino-phenylazo)-benzenesulfonamide are not measurable Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12N-([4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1-naphthyl]methyl)-4-chlorobenzamide 1 mM, 52% inhibition Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12N-([4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1-naphthyl]methyl)benzamide 1 mM, 59% inhibition Go to the Ligand Summary Page
Show all pathways known for 4.6.1.12Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.12N-[4-[(6-aminopyridin-3-yl)amino]-3-methylbenzyl]-4-(trifluoromethyl)benzamide 1 mM, 60% inhibition Go to the Ligand Summary Page
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