EC Number |
Inhibitors |
Structure |
---|
4.4.1.20 | 2-benzoyl-5-[5-[(4-chlorophenyl)(methyl)amino]pyridine-2-carbonyl]benzoic acid |
potent and selective inhibitor, potently inhibits cysteinyl leukotriene biosynthesis in immune cells |
|
4.4.1.20 | 5-[5-[(4-chlorophenyl)(methyl)amino]pyridine-2-carbonyl]-2-(4-methoxybenzoyl)benzoic acid |
tandem benzophenone amino pyridine inhibitor |
|
4.4.1.20 | 5-[5-[(4-chlorophenyl)(methyl)amino]pyridine-2-carbonyl]-2-(4-methoxybenzoyl)benzoic acid |
potent and selective inhibitor, potently inhibits cysteinyl leukotriene biosynthesis in immune cells |
|
4.4.1.20 | 5-[5-[(4-chlorophenyl)(cyclopropylmethyl)amino]pyridine-2-carbonyl]-2-(4-methoxybenzoyl)benzoic acid |
compound at 6 mg/kg body weight reduces LTE4 levels in peritoneal lavage fluid by 88%and significantly decreases vascular permeability in vivo. Potent and selective inhibitor, potently inhibits cysteinyl leukotriene biosynthesis in immune cells |
|