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EC Number
Inhibitors
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Structure
4.4.1.20
Sulfobromophthalein
IC50: 0.06 mM
4.4.1.20
Triphenyltin chloride
poor inhibitor
4.4.1.20
Tumor necrosis factor alpha
-
4.4.1.20
zymosan
increase in LTC4S activity during differentiation of monocytic Mono Mac 6 cells by presence of leukotriene A4 is reduced by 80% in the presence of zymosan. Treatment with Zymosan for 48 h similarly attenuates LTC4S activity of primary human monocyte-derived macrophages and dendritic cells
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