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<< < Results 11 - 20 of 40 > >>
EC Number Inhibitors Commentary Structure
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11acetyl-CoA CoA-dependent interaction of PanZ and PanD. Growth inhibition is due to the CoA-dependent PanD-PanZ interaction and the inhibition occurs at native concentrations of PanD and PanZ in the cell. The production of beta-alanine is feedback-regulated by the PanZ-AcCoA complex Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11beta-hydroxy-DL-Asp - Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11CoA the CoA-dependent interaction inhibits catalysis by the activated enzyme. Binding of acetyl-CoA to PanZ is required to form the PanZ/PanD interface. PanZ.AcCoA inhibits the activated enzyme regulating pantothenate biosynthesis. The binding site for AcCoA is very close to the protein-protein interface. Structure of the complex of PanD and its activating factor PanZ with bound CoA, overview Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11CuCl 10 mM, 88% inhibition Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11D-Ser - Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11D-tagatose ZINC03830878, weak inhibition Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11D-Tartrate ZINC00895296, strong inhibition Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11DL-threo-beta-hydroxyaspartate strong inhibition Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11hydroxylamine - Go to the Ligand Summary Page
Show all pathways known for 4.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.11KCl 200 mM, 63% inhibition Go to the Ligand Summary Page
<< < Results 11 - 20 of 40 > >>