EC Number |
Inhibitors |
Structure |
---|
3.5.3.18 | (2S)-2-amino-5-[N'-(but-3-yn-1-yl)carbamimidamido]pentanoic acid |
- |
|
3.5.3.18 | (2S)-2-amino-5-[N'-(nitromethyl)carbamimidamido]pentanoic acid |
- |
|
3.5.3.18 | (2S)-2-amino-5-[N'-(pent-4-en-1-yl)carbamimidamido]pentanoic acid |
- |
|
3.5.3.18 | 2,3-dimethoxy-1,4-naphthoquinone |
1 mM |
|
3.5.3.18 | 2-(N,N-diethylamino)-diazenolate-2-oxide |
1 mM |
|
3.5.3.18 | 2-(N,N-dimethylamino)-diazenolate-2-oxide |
S-nitrosylation of apo-enzyme, holo-enzyme resists, reaction with two of five Cys-residues |
|
3.5.3.18 | 2-(N,N-dimethylamino)-diazenolate-2-oxide |
i.e. DEANONOate, inhibition by S-nitrosylation, reversed by dithiothreitol |
|
3.5.3.18 | 2-(N,N-dimethylamino)diazenolate-2-oxide |
1 mM, 50% inhibition of DDAH-1 |
|
3.5.3.18 | 2-(N,N-dimethylamino)diazenolate-2-oxide |
1 mM, 50% inhibition of DDAH-1; 1 mM, 50% inhibition of DDAH-1 |
|
3.5.3.18 | 2-amino-4-(NG-methyl-guanidino)butanoic acid |
incubation of lysed red blood cells, dose dependent inhibition of NG,NG-dimethyl-L-arginine degradation with the highest dose (1 mM) reversing the pattern to a net increase in NG,NG-dimethyl-L-arginine concentration for the 1- and 3h time points |
|