EC Number |
Inhibitors |
Structure |
---|
3.4.15.1 | more |
the purified mucilage of storage roots (Ipomoea batatas (L.) Lam. Tainong 57) exhibits dose-dependent ACE inhibitory activity in vitro. The mucilage acted as a mixed type inhibitor toward ACE with an IC50 of 0.3645 mg/ml |
|
3.4.15.1 | captopril |
the relative potency of the inhibitors in the order of decreasing efficieny is: enalaprilat, lisinopril, captopril. The thermodynamic behaviour of the binding process is analyzed |
|
3.4.15.1 | enalaprilat |
the relative potency of the inhibitors in the order of decreasing efficieny is: enalaprilat, lisinopril, captopril. The thermodynamic behaviour of the binding process is analyzed |
|
3.4.15.1 | lisinopril |
the relative potency of the inhibitors in the order of decreasing efficieny is: enalaprilat, lisinopril, captopril. The thermodynamic behaviour of the binding process is analyzed |
|
3.4.15.1 | more |
the two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors |
|
3.4.15.1 | lisinopril |
therapeutic resistance to angiotensin converting enzyme inhibition is related to a difference in the combination of renal pharmacodynamic and pharmacokinetic characteristics in non-responders, primarily consisting of increased renal expression of angiotensin converting enzyme and higher angiotensin converting enzyme inhibitor clearance |
|
3.4.15.1 | Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro |
therapeutical useful |
|
3.4.15.1 | quinapril |
tissue angiotensin converting enzyme inhibitors |
|
3.4.15.1 | more |
tissue angiotensin converting enzyme inhibitors exert more pronounced antithrombotic effect than plasma ACE-Is in experimental thrombosis |
|
3.4.15.1 | enalapril |
treatment of mdx mice (murine model of duchenne muscular dystrophy) with the ACE inhibitor enalapril significantly increases the net force and tetanic isometric force of the gastrocnemius muscle in sedentary and exercised dystrophic mice. Enalapril decreases the necrotic areas in the gastrocnemius muscles in both conditions of mdx mice. ACE inhibition treatment also leads to a decrease in fibrosis, as manifested by a reduction in ECM protein levels and collagen amount |
|