EC Number   |
Inhibitors |
Structure |
|---|
    2.8.1.6 | L-methionine |
product inhibition. The combination of both products in equimolar concentrations results in more than simple additive inhibition, suggesting that they bind cooperatively to the enzyme. |
   |
| 2.8.1.6 | more |
not inhibitory: pyridoxal 5-phosphate, deoxyadenosine |
|
| 2.8.1.6 | more |
5'-methylthioadenosine is not an inhibitor. Neither biotin nor iminobiotin is a significant inhibitor |
|
| 2.8.1.6 | NaBH4 |
decreases cysteine desulfurase and biotin synthase activity |
|
| 2.8.1.6 | S-(5'-adenosyl)-L-cysteine |
competitive |
|
| 2.8.1.6 | S-(5'-adenosyl)-L-homocysteine |
competitive |
|
| 2.8.1.6 | S-adenosyl-L-homocysteine |
potent inhibitor |
|
| 2.8.1.6 | sinefungin |
- |
|
| 2.8.1.6 | Zn2+ |
1 mM, almost complete inhibition |
|
