EC Number   |
Inhibitors |
Structure |
|---|
   2.7.11.10 | (E)-4-[3-(5-adamant-1-yl-4-(2-methoxyethoxymethoxy)-2-(prop-1-oxy)-phenyl)-3-oxoprop-1-en-1-yl]benzoic acid |
- |
   |
| 2.7.11.10 | (R)-2-amino-4-(2-(hydroximethyl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
- |
|
| 2.7.11.10 | (R)-2-amino-4-(3-hydroxypyrrolidin-1-yl)-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonitrile |
- |
|
| 2.7.11.10 | (S)-2-amino-4-(2-(hydroximethyl)pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
- |
|
| 2.7.11.10 | 1-(2-amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-sulfonamide |
- |
|
| 2.7.11.10 | 1-(4-chlorophenyl)-4-ureido-1H-pyrazole-3-carboxamide |
i.e. SC-108 |
|
| 2.7.11.10 | 1-(6-chloro-9H-beta-carbolin-8-yl)-3-methylurea |
inhibits IKK with IC50 of 0.02 mM |
|
| 2.7.11.10 | 1-(benzo[d][1,3]dioxol-5-yl)-8-(3-chloroisonicotinamido)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide |
i.e. PHA-379 |
|
| 2.7.11.10 | 1-(benzo[d][1,3]dioxol-5-yl)-8-(5-chloro-2-(4-methylpiperazin-1-yl)isonicotinamido)-4,5-dihydro-1H-benzo-[g]indazole-3-carboxamide |
i.e. PHA-250 |
|
| 2.7.11.10 | 1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol |
NCI0288748, 65% inhibition at 0.1 mM |
|
