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EC Number Inhibitors Commentary Structure
Display the reaction diagram Show all sequences 2.3.1.301more 2-tosylnaphthalene-1,4-diol analogues are reversible inhibitors (30 nM-5 microM) of the Mycobacterium tuberculosis and Plasmodium falciparum FabH enzymes. The sulfonyl group and naphthalene-1,4 diol are required for activity against all enzymes but the toluene portion can be significantly altered. Inhibitors are also effective against Escherichia coli FabH, EC 2.3.1.180 Go to the Ligand Summary Page
Display the reaction diagram Show all sequences 2.3.1.301more not inhibitory: cerulenin Go to the Ligand Summary Page
Display the reaction diagram Show all sequences 2.3.1.301thiolactomycin - Go to the Ligand Summary Page
Display the reaction diagram Show all sequences 2.3.1.301[4-(1,4-dihydroxynaphthalene-2-sulfonyl)phenyl]carbamic acid - Go to the Ligand Summary Page
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