EC Number   |
Inhibitors |
Structure  |
|---|
    1.5.5.2 | L-azetidine-2-carboxylate |
competitive |
   |
| 1.5.5.2 | thiazolidine-2-carboxylate |
a mechanism-based inactivator of PRODH. PRODH catalyzes the oxidation of thiazolidine-2-carboxylate at the C atom adjacent to the S atom of the thiazolidine ring (C5). Then, the N5 atom of the reduced FAD attacks the C5 of the oxidized T2C species, resulting in a covalent adduct |
|
| 1.5.5.2 | L-thiazolidine-4-carboxylate |
competitive |
|
| 1.5.5.2 | 5-ethylpentyl-barbituric acid |
membrane-associated enzyme, not soluble enzyme |
|
| 1.5.5.2 | pyrrolidone-5-carboxylate |
- |
|
| 1.5.5.2 | GuHCl |
enzyme unfolding at 1 M, 0.5 M is not enough for proper unfolding. The fusion protein forms visible aggregates due to unfolding of MBP |
|
