EC Number |
Inhibitors |
Structure |
---|
1.5.5.2 | 2-Thenoyltrifluoroacetone |
an inhibitor of Complex II, addition of TTFA significantly reduces PRODH/POX activity |
|
1.5.5.2 | acetate |
competitive |
|
1.5.5.2 | L-azetidine-2-carboxylate |
competitive |
|
1.5.5.2 | L-lactate |
competitive |
|
1.5.5.2 | L-tetrahydro-2-furoic acid |
competitive |
|
1.5.5.2 | L-thiazolidine-4-carboxylate |
competitive |
|
1.5.5.2 | GuHCl |
enzyme unfolding at 1 M, 0.5 M is not enough for proper unfolding. The fusion protein forms visible aggregates due to unfolding of MBP |
|
1.5.5.2 | N-propargylglycine |
irreversibly inactivates PutA by covalently linking the flavin N(5) atom to the epsilon-amino of Lys329. Inactivation locks PutA into a conformation that may mimic the proline-reduced, membrane-associated form |
|
1.5.5.2 | 5-ethylpentyl-barbituric acid |
membrane-associated enzyme, not soluble enzyme |
|
1.5.5.2 | more |
no enzyme inhibibtion by atpenin A5, an inhibitor of Complex II |
|