EC Number   |
Inhibitors |
Structure |
|---|
    1.3.98.1 | Orotate |
competitive |
   |
| 1.3.98.1 | Orotate |
competitively inhibits all three DHOD enzymes to a comparable level |
|
| 1.3.98.1 | orotate methyl ester |
orotate analogue, 50% inhibition at 0.71 mM |
|
| 1.3.98.1 | oxonate |
crystallization data |
|
| 1.3.98.1 | oxonic acid |
orotate analogue, 50% inhibition at 0.0099 mM |
|
| 1.3.98.1 | p-hydroxymercuribenzoate |
98% inhibition after 5 min at 0.00227 mM |
|
| 1.3.98.1 | Salicylhydroxamic acid |
weak inhibition, pH 9.0, 37°C |
|
| 1.3.98.1 | suramin |
weak inhibition, pH 9.0, 37°C |
|
| 1.3.98.1 | Tiron |
inhibits cytochrome c reduction and sulfite autoxidation |
|
| 1.3.98.1 | Uracil |
orotate analogue, 50% inhibition at 2.5 mM |
|
