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EC Number
Inhibitors
Commentary
Structure
1.1.1.22
UDP-xylose
a potent UGDH inhibitor
1.1.1.22
UDP-xylose
allosteric feedback inhibitor, reduces significantly the activity of the enzyme
1.1.1.22
UDParabinose
-
1.1.1.22
UDPgalacturonic acid
-
1.1.1.22
UDPglucuronate
-
1.1.1.22
UDPglucuronate
product feed-back inhibition competitive with UDPglucose
1.1.1.22
UDPxylose
-
1.1.1.22
Urea
strong inhibition
1.1.1.22
Uridine 5'-diphosphate chloroacetol
alkylates a thiol group of cysteine in the catalytic centre via being specifically bound instead of the substrate
1.1.1.22
Zn2+
strong inhibition
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