EC Number   |
Inhibitors |
Structure |
|---|
    1.1.1.22 | more |
enzyme is active in the absence of metal ions |
 |
| 1.1.1.22 | NaCl |
VNG1048G loses much of its activity when salinity drops below 3 M NaCl |
  |
| 1.1.1.22 | NAD+ |
substrate inhibition, reversible by the addition of a nucleotide triphosphate, e.g. ATP, in the absence of kinase. Mutations in a previously identified UDP-glucuronic acid allosteric binding site decrease the binding affinity of the nucleotide triphosphate |
|
| 1.1.1.22 | NADH |
- |
|
| 1.1.1.22 | NADH |
0.1 mM, presence of 0.1 mM NAD+, 44% inhibition, presence of 0.5 mM NAD+, 6% inhibition |
|
| 1.1.1.22 | NADH |
product inhibition, 26% residual activity at 0.05 mM; product inhibition, 70% residual activity at 0.05 mM |
|
| 1.1.1.22 | NADH |
0.05 mM, partial inhibition |
|
| 1.1.1.22 | NH2OH |
deactivation |
|
| 1.1.1.22 | p-chloromercuribenzoate |
- |
|
| 1.1.1.22 | p-chloromercuribenzoate |
0.001 mM, 66% inhibition |
|
