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EC Number Inhibitors Commentary Structure
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8gabaculine 0.0005 mM, 50% inhibition. The inhibition is reversible up to 1 h after its addition, if the gabaculine is removed by gel filtration, before the enzyme is incubated by gel filtration, before the enzyme is incubated with substrate. Irreversible inhibition is obtained by preincubation of the enzyme at 30°C either for several hours with gabaculine alone or for a few min with both gabaculine and glutamate-1-semialdehyde Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8gabaculine - Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8gabaculine wild-type enzyme is inhibited, gabaculine-resistant mutant enzyme is not inhibited Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8gabaculine potent inhibitor Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8glyoxylate 20 mM, 27% inhibition Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8more no inhibition by 3-hydroxyglutamate Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8more 5 mM EDTA has no effect on activity Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8p-chloromercuribenzoate 0.1 mM, 45% inhibition Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8pyridoxal 5'-phosphate 5 mM, 47% inhibition Go to the Ligand Summary Page
Show all pathways known for 5.4.3.8Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.8pyridoxal 5'-phosphate - Go to the Ligand Summary Page
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