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EC Number
Inhibitors
Commentary
Structure
Sulfobromophthalein
IC50: 0.06 mM
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Triphenyltin chloride
poor inhibitor
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Tumor necrosis factor alpha
-
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zymosan
increase in LTC4S activity during differentiation of monocytic Mono Mac 6 cells by presence of leukotriene A4 is reduced by 80% in the presence of zymosan. Treatment with Zymosan for 48 h similarly attenuates LTC4S activity of primary human monocyte-derived macrophages and dendritic cells
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