EC Number |
Inhibitors |
Structure |
---|
2.1.1.157 | L-phenylalanine |
10% inhibition at 250 mM |
|
2.1.1.157 | more |
no inhibition by N,N-dimethylglycine |
|
2.1.1.157 | more |
inhibition rates with sarcosine, overview, no inhibition with dimethylglycine by glycine, acetate, ethanolamine, monomethylethanolamine, serine, asparagine, glutamate, and proline |
|
2.1.1.157 | more |
potassium or sodium ions at 200-1000 mM affect neither sarcosine N-methyltransferase activity nor dimethylglycine N-methyltransferase activity |
|
2.1.1.157 | more |
both the SMT and DMT activities of SDMT from halophilic methanoarchaea are not inhibited by KCl or NaCl |
|
2.1.1.157 | n-butyric acid |
50% inhibition at 250 mM, with dimethylglycine |
|
2.1.1.157 | propionic acid |
10% inhibition at 250 mM, with dimethylglycine |
|
2.1.1.157 | S-adenosyl-L-homocysteine |
recombinant enzyme: competitive product inhibition, 50% inhibition at 0.5 mM with glycine, and at 2.3 mM with sarcosine |
|
2.1.1.157 | S-adenosyl-L-homocysteine |
product inhibition |
|
2.1.1.157 | S-adenosyl-L-homocysteine |
0.2 mM, 63% loss of sarcosine N-methyltransferase activity, 81% loss of dimethylglycine N-methyltransferase activity. At 1 mM, complete loss of sarcosine N-methyltransferase activity, 88% loss of dimethylglycine N-methyltransferase activity |
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