EC Number |
Inhibitors |
Structure |
---|
1.5.5.2 | L-lactate |
a competitive inhibitor of ProDH in plants |
|
1.5.5.2 | D-lactate |
- |
|
1.5.5.2 | D-lactate |
a competitive inhibitor of ProDH in plants |
|
1.5.5.2 | rotenone |
an inhibitor of Complex I, addition of ROT only modestly affects PRODH/POX activity |
|
1.5.5.2 | antimycin A |
very strong inhibition |
|
1.5.5.2 | Lactate |
- |
|
1.5.5.2 | 2-Thenoyltrifluoroacetone |
an inhibitor of Complex II, addition of TTFA significantly reduces PRODH/POX activity |
|
1.5.5.2 | L-tetrahydro-2-furoic acid |
competitive |
|
1.5.5.2 | L-tetrahydro-2-furoic acid |
- |
|
1.5.5.2 | N-propargylglycine |
irreversibly inactivates PutA by covalently linking the flavin N(5) atom to the epsilon-amino of Lys329. Inactivation locks PutA into a conformation that may mimic the proline-reduced, membrane-associated form |
|