EC Number |
Activating Compound |
Reference |
---|
4.6.1.13 | butyl-fluorescein myo-inositol phosphate |
two molecules bind to enzyme, one at the active site and one at a subsite, causing an increase in activity, kinetics |
650586 |
4.6.1.13 | deoxycholate |
- |
285235 |
4.6.1.13 | deoxycholate |
stimulates |
285225 |
4.6.1.13 | diacylglycerol |
activates |
285235 |
4.6.1.13 | diacylglycerol |
activates, increases the hydrolytic activity of PI-PLC on large unilamellar vesicles containing 5-40% phosphatidylinositol |
651281 |
4.6.1.13 | diethyl ether |
strongly activates |
285235 |
4.6.1.13 | diheptanoyl phosphatidylcholine |
activates |
652411 |
4.6.1.13 | dihexanoyl phosphatidylcholine |
activates, 4-5fold increase in catalytic efficiency, binds to a lipid-binding subsite, not to the active site, maximal activation at 0.4 mM |
650573 |
4.6.1.13 | dihexanoylphosphatidylcholine |
non-substrate activator lipid, maximum PI-PLC activity at 0.7-1 mM |
650586 |
4.6.1.13 | dimethylformamide |
water-miscible, enhances phosphotransferase activity |
650390 |