EC Number   |
Activating Compound |
Reference |
|---|
   4.2.1.167 | (R)-2-hydroxyglutaryl-CoA dehydratase component A |
- |
733766 |
| 4.2.1.167 | (R)-2-hydroxyglutaryl-CoA dehydratase component A |
activator protein, UniProt ID Q9X5B6 |
733328 |
| 4.2.1.167 | Activator protein |
the enzyme must be activated by an activator protein. Once activated, it can catalyse many turnovers |
733761 |
| 4.2.1.167 | activator protein HgdC |
- |
733328 |
| 4.2.1.167 | activator protein HgdC |
the enzyme is activated by ATP, MgCl2, and Ti(III)citrate by an activator protein (HgdC) that is present in the organism at very low concentrations. It is suggested that during the activation step, the electron of this cycle is fed into the enzyme by Ti(III)citrate and energized by hydrolysis of ATP. Both functions are apparently catalysed by the activator. The enzyme remains in this activated state for several turnovers |
738150 |
| 4.2.1.167 | FMNH2 |
1 mol per mol heterodimeric enzyme |
733766 |
| 4.2.1.167 | FMNH2 |
1.0 mol per mol of heterodimeric enzyme |
733328 |
| 4.2.1.167 | more |
enzyme requires an activator protein HgdC for activity. Dehydratase activity is stimulated at least tenfold by cell-free extracts of Escherichia coli cells transformed with a plasmid carrying hgdC. On the chromosome the HgdC gene is located just before the catalytic subunits hgdA and hgdB |
738220 |
| 4.2.1.167 | riboflavin |
0.3 mol per mol heterodimeric enzyme |
733766 |
| 4.2.1.167 | riboflavin |
0.3 mol per mol of heterodimeric enzyme |
733328 |
