EC Number   |
Activating Compound |
Reference |
|---|
    4.1.1.22 | Butyrate |
highly activating for the wild-type enzyme |
680763 |
| 4.1.1.22 | C/EBPbeta |
essential for the HDC induction |
690778 |
| 4.1.1.22 | ethanol |
does not increase hdc gene expression or activity in cells, but increases HDC activity |
692809 |
| 4.1.1.22 | ethanol |
does not increase hdc gene expression or activity in cells, but increases HDC activity, 122% activity at 10% ethanol |
692809 |
| 4.1.1.22 | gastrin |
increase of steady-state levels of 6 HDC isoforms |
652502 |
| 4.1.1.22 | HdcB |
HdcB catalyses the maturation of pyruvoyl-dependent histidine decarboxylase by cleavage of the proenzyme which results in the formation of the pyruvoyl prosthetic group |
716264 |
| 4.1.1.22 | lipopolysaccharide |
excreted from Escherichia coli after oral infection, stimulates the enzyme in dental pulp and gingiva, tissue-specific effects, oveview |
677857 |
| 4.1.1.22 | monosodium urate |
monosodium urate crystals injected into the air pouch lead to a highly upregulated mRNA level of HDC |
690666 |
| 4.1.1.22 | more |
12-O-tetradecanoylphorbol-13-acetate induces the enzyme |
679733 |
| 4.1.1.22 | more |
antigen challenge induces HDC in both mast cell-dependent and mast cell-independent ways at a postanaphylactic time in the liver, lung, spleen, and ears, enzyme activity is increased in atissue-dependent manner after sensitization of wild-type mice by ovalbumin, overview |
680165 |
