EC Number   |
Activating Compound |
Reference |
|---|
   3.4.24.B4 | 12-O-tetradecanoyl phorbol 13-acetate |
8fold activation of transcriptional activity in chondrocytes |
650906 |
| 3.4.24.B4 | amino phenylmercuric acetate |
activation |
651876 |
| 3.4.24.B4 | angiotensin II |
- |
711052 |
| 3.4.24.B4 | hepatocyte growth factor |
stimulation of enzyme expression in osteoarthritic chondrocytes |
650906 |
| 3.4.24.B4 | integrins |
e.g. integrin alpha1beta and alpha2beta1, induction via MAPkinase |
650906 |
| 3.4.24.B4 | interleukin-1 |
alpha and beta form, induction of enzyme expression, which is inhibited by 15-deoxy-DELTA12,14-prostaglandin J2, induction of enzyme expression in chondrosarcoma cells requires nuclear factor-kappaB nuclear translocation, p38 MAPkinase activity, c-Jun N-terminal kinase activity |
650906 |
| 3.4.24.B4 | interleukin-1alpha |
10 ng/ml |
680858 |
| 3.4.24.B4 | interleukin-1beta |
activates, hyaluronan inhibits interleukin-1beta-stimulated MMP-13 via CD44 in arthritic chondrocytes |
712838 |
| 3.4.24.B4 | more |
the prodomain of MMP13 determines autoactivation of MMP13 and intracellular degradation of MMP13 |
710801 |
| 3.4.24.B4 | oncostatin |
induction of enzyme expression, requires phosphorylation of JAK3 |
650906 |
