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Results 1 - 10 of 18 > >>
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more antibodies that recognize domains T67, T8, and CUB domains have additive effects. Binding activates ADAMTS13 up to 4.2fold at pH 7.4, but antibodies have markedly decreased effects on ADAMTS13 activity at pH 6 735184
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more CCl4 at concentration of 6.5 mM does not directly enhance the activity of ADAMTS-13 670063
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more cleavage of von Willebrand factor A2 requires the force-induced A2 unfolding 711576
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more coagulation factor VIII, platelet glycoprotein 1balpha, and heparin sulfate accelerate the cleavage of von Willebrand factor 720833
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more in the absence of factor VIII, lyophilized platelets increase the formation of cleavage product by 2-3fold under fluid shear stresses. However, in the presence of physiological concentration of factor VIII (1 nM), the formation of von Willebrand factor cleavage product increases dramatically as a function of increasing platelets (150000 per microliter) with the maximal rate enhancement of about 8fold 719881
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more inhibition of ADAMTS13 by auto-antibodies is reversed by rituximab, overview 713531
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more low salt concentrations activate the proteolytic activity 650717
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more mild denaturation of fluid shear stress increase the hydrolysis of von Willebrand factor 711809
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more removal of the C-terminal domain of the enzyme by activated coagulation factor XI or alpha-thrombin causes an increase in enzyme activity 753666
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.87more substrate modified by alpha2-3,6,8,9-neuraminidase from Arthrobacter ureafaciens removing alpha2-3- and alpha2-6-linked sialic acid results in reduced ADAMTS13 activity 711575
Results 1 - 10 of 18 > >>