EC Number   |
Activating Compound |
Reference |
|---|
   3.4.24.82 | C-terminal thrombospondin type I motif of ADAMTS-5 |
addition of the C-terminal thrombospondin type I motif of ADAMTS-5 to the C terminus of ADAMTS-4 increases the activity of ADAMTS-4 against aggrecan and fibromodulin severalfold |
680923 |
| 3.4.24.82 | glycosylphosphatidyl inositolanchored membrane type 4-matrix metalloproteinase |
MT4-MMP or also called MMP-17 |
669205 |
| 3.4.24.82 | IL-1beta |
10 ng/ml, 20 min, upregulation of ADAMTS-4 only in presence of adaptor proteins MyD88, IRAK1 and TRAF6 |
699350 |
| 3.4.24.82 | interferon gamma |
- |
677894 |
| 3.4.24.82 | interleukin-1 |
- |
679302 |
| 3.4.24.82 | interleukin-1alpha |
- |
697932 |
| 3.4.24.82 | interleukin-1alpha |
increase of ADAMTS-4 in wild-type mice |
695954 |
| 3.4.24.82 | interleukin-1alpha |
induced gene expression in osteoarthritic chondrocytes |
695608 |
| 3.4.24.82 | interleukin-1beta |
10 ng/ml |
678446 |
| 3.4.24.82 | more |
4.2fold enhanced expression during infection with Borrelia burgdorferi |
667360 |
