EC Number   |
Activating Compound |
Reference |
|---|
   3.4.24.56 | 1-diphosphoinositol pentakisphosphate |
activates, maximal 79.7fold activation |
755263 |
| 3.4.24.56 | 2',3'-O-(2,4,6-trinitrophenyl)adenosine triphosphate |
about 15fold activation, 50% activation at o.0016 mM, activation is inhibited by Mg2+ |
667327 |
| 3.4.24.56 | 2'-O-(2,4,6-trinitrophenyl) adenosine triphosphate |
ATP-derivative TNP-ATP |
683150 |
| 3.4.24.56 | 3'-O-(2,4,6-trinitrophenyl) adenosine triphosphate |
ATP-derivative TNP-ATP |
683150 |
| 3.4.24.56 | 5-(4-chlorophenyl)-2-[(E)-{[(5-chloro-1,2,3-thiadiazol-4-yl)methoxy]imino}methyl]cyclohexane-1,3-dione |
direct stimulation of IDE, acts highly synergistically with ATP, Ia1 activates the degradation of amyloid beta by about 700% in presence other shorter substrates |
710361 |
| 3.4.24.56 | 5-diphosphoinositol pentakisphosphate |
activates, maximal 94.7fold activation |
755263 |
| 3.4.24.56 | A23187 |
calcium ionophore, increases extracellular IDE activity, but only under conditions that also elicit cytotoxicity |
700288 |
| 3.4.24.56 | ADP |
activates, the activating effect of ATP is greater than hat of ADP, which in turn is much greater than that of AMP |
683651 |
| 3.4.24.56 | ADP |
in Tris buffer, activation for substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine). Activation in decreasing order: ATP, triphosphate, ADP, AMP |
669298 |
| 3.4.24.56 | ADP |
inhibition of binding of 2,3-O-(2,4,6-trinitrophenyl)adenosine triphosphate with Ki-value 2.2 mM |
667327 |
