EC Number   |
Activating Compound |
Reference |
|---|
   3.4.24.15 | 2-mercaptoethanol |
activates at low concentrations |
37055 |
| 3.4.24.15 | 2-mercaptoethanol |
enzyme that has been exposed to air in solution lacking thiol compounds shows very marked stimulation of activity by low concentrations of 2-mercaptoethanol |
37063 |
| 3.4.24.15 | Calmodulin |
interaction with calmodulin is important for the secretion of thimet oligopeptidase following stimulation. Overexpression of calmodulin in HEK293 cells is sufficient to greatly increase the A23187-stimulated secretion of EP24.15, which can be inhibited by the calmodulin inhibitor calmidazolium |
708478 |
| 3.4.24.15 | Calmodulin/Ca2+ |
Ca2+-dependent interaction with calmodulin is important for the secretion of thimet oligopeptidase following stimulation. Overexpression of calmodulin in HEK293 cells is sufficient to greatly increase the A23187-stimulated secretion of EP24.15, which can be inhibited by the calmodulin inhibitor calmidazolium |
708478 |
| 3.4.24.15 | cocaine |
cocaine treatment causes an increase in the ventral striatum in enzyme specific activity and enzyme relative mRNA amount determined by real time RT-PCR |
733250 |
| 3.4.24.15 | dithiothreitol |
activates at low concentrations |
37055 |
| 3.4.24.15 | dithiothreitol |
enzyme that has been exposed to air in solution lacking thiol compounds shows very marked stimulation of activity by low concentrations of dithiothreitol |
37063 |
| 3.4.24.15 | GSSG |
enzyme oligomerization, induced by S-glutathionylation, has a regulatory function, maximal activity by partial S-glutathionylation, overview |
683488 |
| 3.4.24.15 | H2O2 |
- |
753583 |
| 3.4.24.15 | H2O2 |
synergistic effect of antimycin A, succinate, and antimycin A plus succinate on activation by H2O2. Antimycin A and succinate stimulate the H2O2 production and increase rTOP activity |
753583 |
