EC Number |
Activating Compound |
Reference |
---|
3.4.22.41 | Brij 35 |
273.6% relative activity at 0.01% (v/v) |
708220 |
3.4.22.41 | chondroitin-4-sulfate |
activates apoB-100/LDL degradation by cathepsin F |
669249 |
3.4.22.41 | chondroitin-6-sulfate |
activates apoB-100/LDL degradation by cathepsin F |
669249 |
3.4.22.41 | dermatan sulfate |
activates apoB-100/LDL degradation by cathepsin F |
669249 |
3.4.22.41 | heparan sulfate |
activates apoB-100/LDL degradation by cathepsin F |
669249 |
3.4.22.41 | human aortic proteoglycans |
activates apoB-100/LDL degradation by cathepsin F |
669249 |
3.4.22.41 | more |
cathepsin F is secreted as an inactive zymogen that autocatalytically processes and activates to a mature enzyme at pH 4.5 (after 6 h incubation) via an intermolecular cleavage at the prosegment-mature domain junction, the active cathepsin B1 zymogen is capable of trans-activating cathepsin F by proteolytic removal of its prosegment at pH 5.5 |
708053 |
3.4.22.41 | Triton X-100 |
310.29% relative activity at 0.01% (v/v) |
708220 |
3.4.22.41 | Tween 20 |
282.7% relative activity at 0.01% (v/v) |
708220 |