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EC Number	Activating Compound	Commentary	Reference
3.4.21.89	Aprotinin	-	651885
3.4.21.89	bestatin	-	651885
3.4.21.89	dodecylphosphocholine	at 37°C, degradation occurs to a lesser extent in dodecylphosphocholine micelles than in Triton X-100 or n-octyl-beta-D-glucopyranoside	696392
3.4.21.89	EDTA	-	651885
3.4.21.89	EGTA	-	651885
3.4.21.89	Elastinal	-	651885
3.4.21.89	more	no significant difference in expression levels in the presence and absence of deuterium oxide. Elevated temperature enhances enzyme degradation, at 37°C, the protein is autolysed and degraded more than at 22°C	696392
3.4.21.89	more	the activity of the truncated SpsB increases in the presence of a non-ionic detergent	708475
3.4.21.89	n-octyl-beta-D-glucopyranoside	-	696392
3.4.21.89	phosphatidylethanolamine	is required to maintain activity of the membrane-incorporated signal-peptidase (full-length signal peptidase I incoporated into phospholipid vesicles). Maximal activity is achieved at about 55% phosphatidylethanolamine	667597

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Release 2023.1 (January 2023)