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EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.84lipopolysaccharide - 652485
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.84lipopolysaccharide Escherichia coli serotype O55:B5 lipopolysaccharide (LPS) is used with a potency of 10 EU/ng, structure analysis, reconstitution of lyophilized LPS into solution. Factor C is activated through lipopolysaccharide. The state of aggregation of LPS impacts factor C activation, particularly in the presence of select salts and non-ionic surfactants that are commonly incorporated into pharmaceutical formulations. Analysis of aggregation status of LPS in aqueous solution using angle-dependent static and dynamic light scattering with and without chelating salts and polysorbate surfactants, and its correlation with activation of factor C, overview. Modulating effects of salts and surfactants on activation of factor C is associated with changes in the LPS aggregation 754261
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.84lipopolysaccharide factor C activation through lipopolysaccharide assay. Detection of various LPS structural species by rFC-based assay. Several bacterial species are used as sources for endotoxin/lipopolysaccharide, overview. Highest activity is obtained with Escherichia coli LPS O111:B4 and J5, lowest activity with LPS from Francisella tularensis or Salmonella lipid A. Induction of interleukin IL-6 by various LPS structural species 754404
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.84more the zymogen factor C shows autocatalytic activation in presence of bacterial lipopolysaccharide 29790, 29791
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