EC Number   |
Activating Compound |
Reference |
|---|
   3.4.21.109 | 4,4'-diisothiocyanatostilbene-2,2' disulfonic acid |
as an early response to acidosis, matriptase activation can also be induced by perturbation of intracellular pH homeostasis using substances inhibiting Na+/H+ exchangers or other acid-base ion channels |
709136 |
| 3.4.21.109 | 5-(N-ethyl-N-isopropyl)-amiloride |
as an early response to acidosis, matriptase activation can also be induced by perturbation of intracellular pH homeostasis using substances inhibiting Na+/H+ exchangers or other acid-base ion channels |
709136 |
| 3.4.21.109 | 5-(N-methyl-N-isobutyl)-amiloride |
as an early response to acidosis, matriptase activation can also be induced by perturbation of intracellular pH homeostasis using substances inhibiting Na+/H+ exchangers or other acid-base ion channels |
709136 |
| 3.4.21.109 | C2 ceramide 1-phosphate |
weaker activator than sphingosine 1-phosphate, activation at 0.000237 mM |
652223 |
| 3.4.21.109 | C8 ceramide 1-phosphate |
weaker activator than sphingosine 1-phosphate, activation at 0.001 mM |
652223 |
| 3.4.21.109 | dihydrosphingosine 1-phosphate |
weaker activator than sphingosine 1-phosphate |
652223 |
| 3.4.21.109 | enterokinase |
- |
698665 |
| 3.4.21.109 | Epidermal growth factor |
stimulates the release of matripase/hepatocyte growth factor activator inhibitor-1 complexes |
675024 |
| 3.4.21.109 | H+ |
exposure of epithelial and carcinoma cells to a mildly acidic extracellular milieu pH 6.0 results in robust matriptase activation |
709136 |
| 3.4.21.109 | hepatocyte growth factor activator inhibitor |
HAI-1, zymogen activator of matriptase |
695463 |
