EC Number |
Activating Compound |
Reference |
---|
3.4.15.1 | cetyltrimethylammonium bromide |
0.1 and 1 mM |
732845 |
3.4.15.1 | cetyltrimethylammonium bromide |
CTAB, activates at 0.1-1.0 mM |
755273 |
3.4.15.1 | Cl- |
- |
81241, 81260, 81287 |
3.4.15.1 | Cl- |
activates |
650267, 81212, 81214, 81250, 81264, 81270, 81284 |
3.4.15.1 | Cl- |
activation, optimal NaCl concentration for the brain enzyme in hydrolysis of LVVYPWTQRY is 10 mM, optimal concentration for hydrolysis of angiotensin I is 200 mM |
653416 |
3.4.15.1 | Cl- |
assay in the presence of zinc and chloride |
764572 |
3.4.15.1 | Cl- |
kcat increases with increasing KCl concentrations, reaches a maximum at about 300 mM KCl, and the begins to decrease. At relatively low concentrations chloride anions activate the C-domain of the enzyme, but at high concentrations chloride inhibits the enzyme activity. Presence of at least two chloride-binding sites in the C-domain of bovine enzyme: binding of chloride to one of the sites causes activation of the enzyme, whereas chloride binding to the second site results in inhibition of the enzymatic activity |
667760 |
3.4.15.1 | Cl- |
nonessential activator over the pH range 5.0-10.0 |
81233 |
3.4.15.1 | Cl- |
required |
81213, 81247, 81251, 81259 |
3.4.15.1 | Cl- |
required for hydrolysis of angiotensin I, not required for hydrolysis of bradykinin |
81241 |